BEST SKIN LIGHTENING TREATMENT @ dermi_glow Villivakkam Chennai: Skin whitening agents work by reducing the presence of melanin pigment in the skin. Other motivations for skin whitening include desiring softer skin and wanting to conceal discolorations arising from pimples, rashes, or chronic skin conditions. Skin whitening agents work by reducing the presence of melanin pigment in the skin. To accomplish this, there are several possible mechanisms of action. Inhibition of tyrosinase. MC1R is an important target for the regulation of melanogenesis. Agonism of MC1R increases the ratio of eumelanin to pheomelanin and increases the generation of melanin overall. What is MC1R? Melanocortin 1 receptor, it is one of the key proteins involved in regulating mammalian skin and hair color. It is located on the plasma membrane of specialized cells known as melanocytes, which produce the pigment melanin through the process of melanogenesis. This receptor plays an important role in normal pigmentation. The receptor is primarily located on the surface of melanocytes, which are specialized cells that produce a pigment called melanin. In the human skin, melanogenesis is initiated by exposure to UV radiation, causing the skin to darken. There are three basic types of melanin in human : eumelanin, pheomelanin and neuromelanin. The most common type is eumelanin, of which there are two types— brown eumelanin and black eumelanin. Pheomelanin - A type of melanin pigment that is made up of benzothiazine units and is responsible for yellow and pink to red hues or pigmentations such as in hair, lips. Neuromelanin (NM) is a dark pigment found in the brain which is structurally related to melanin. NM is a mixture of pheomelanin and eumelanin, the two major forms corresponding to the widely known light-haired and dark-haired phenotypes, respectively.  Melanin is a class of pigment responsible for producing colour in the body in places such as the eyes, skin, and hair. As the body ages, melanocyte distribution becomes less diffuse and its regulation less controlled by the body. UV light stimulates melanocyte activity, and where concentration of the cells is greater, hyperpigmentation occurs. Contact for further information ...